SNX6 anticorps (Middle Region)

N° du produit ABIN2790092

Cet anticorps Lapin Polyclonal détecte spécifiquement SNX6 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour SNX6 anticorps (Middle Region) (ABIN2790092)

Antigène: SNX6 (Sorting Nexin 6 (SNX6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SNX6 anticorps

Épitope: Middle Region

Séquence: DGVIVSGVKD VDDFFEHERT FLLEYHNRVK DASAKSDRMT RSHKSAADDY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against SNX6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human SNX6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 418 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNX6

Antigène: SNX6 (Sorting Nexin 6 (SNX6))

Autre désignation: SNX6

Sujet: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
Alias Symbols: MGC3157, MSTP010, TFAF2
Protein Interaction Partner: UBC, FAM129B, VPS35, VPS29, RTF1, ATG7, TSNAX, TSN, STAT1, SNX2, SHMT2, SHMT1, PAWR, H3F3A, GTF2A1, ATP6V1C1, APEH, ANP32E, CSNK2A2, SNX1, BRCA1, PHLPP1, COIL, GIT1, ELAVL1, NDEL1, DISC1, TNIK, CALM1, TPT1, SNX6, SNX4, BMPR1B, ACVR2B, ACVRL1, LEPR, TGFBR2
Protein Size: 418

Poids moléculaire: 48 kDa

ID gène: 58533

NCBI Accession: NM_152233, NP_689419

UniProt: Q9UNH7

Pathways: EGFR Signaling Pathway